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Women go through many changes during their lives, and menopause is one of the most important. Conjugated estrogens can help guide a woman through this graceful transition. Conjugated estrogens is a drug consisting of a mixture of Conjugated estrogens isolated from mare’s urine, and comes in the category of drugs used for the treatment of menopausal symptoms. Conjugated estrogens received FDA approval as a hormone replacement therapy in 1995.

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How Conjugated estrogens work?

Estrogen is a sex hormone produced in the body of a woman in ovaries. Woman's ovaries produce less estrogen as they get older. The decreasing level of estragon in a woman's body may lead to serious consequences including bone fragility. Premarin is one of the most common brands of conjugated equine estrogens (CEE). It works by inducing certain hormones that are the cause of this menopausal problems.

The right dosage

Conjugated estrogens come as a cream and as maroon tablets that contain 0.625 mg conjugated oestrogens. Premarin is taken with a glass of water, with or without food at approximately the same time daily. Premarin is generally recommended to be taken in the dose of 1 tablet per day. No specific time period has been identified for the intake of conjugated estrogens because the duration of conjugated estrogens intake depends from individual to individual but the usual course of treatment lasts for about 3 weeks with a week’s break after.

Before using Conjugated estrogens

Conjugated estrogens are most commonly used for the treatment of Menopausal symptoms in women. Long-term estrogens increases the risk of a heart attack, dementia and breast cancer. The risk of cancer of the ovary is also increased by estrogens. To prevent heart disease or dementia, it is recommended not to use Estrogen-containing products. Conjugated estrogens may cause inborn defects. Breastfeeding is not recommended during the treatment. To reduce the risk of endometrial hyperplasia your doctor may prescribe you Progestin to be taken together with Premarin.

Warnings & Precautions

There are chances that any other medicines or medical conditions may interact with this medicine therefore all prescription and over-the-counter medicine that you are taking should be known by your doctor or pharmacist. If you are extremely overweight or have experienced excessive weight gain after starting to take Premarin, or you have any allergies, pregnancy, or breast-feeding than immediately inform your doctor. If you have a history of estrogen-dependent growths, blood clots, liver problems, porphyria, stroke or heart attack, it is recommended not to use this medicine.

What side effects may occur?

You should be aware that there are harmful and debilitating Premarin side effects. Allergy is one of the least dangerous side effects when using conjugated estrogens. Allergic reaction is characterized by troubled breathing, swollen face, throat, lips, tongue. As for the other drugs, the above side effects may or may not be present in every one who is taking Premarin, Cenestin or other conjugated estrogens. Side effects of conjugated estrogens may include: intense sweating; irregular menstruation; irritable mood swings; enlargement of benign tumors of the uterus; hair loss; headache; high blood pressure; high blood sugar; liver problems, nausea and vomiting.