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Clopidogrel, sold as Plavix in the US, Canada and UK, is an anti clotting medicine that works by preventing the platelets in the blood from clustering. This medicine is mostly prescribed for patients suffering from or prone to: heart attacks, stroke, blood clotting and acute coronary heart syndromes. Clopidogrel was approved by the FDA in 1997.

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Clopidogrel Drug Information

Plavix keeps blood platelets slippery and discourages formation of clots, thereby improving blood flow to your heart, brain, and body. The drug is prescribed to reduce the risk of heart attack, stroke, and serious circulation problems in people with hardening of the arteries or unstable angina (dangerous chest pain), and in people who've already suffered a heart attack or stroke.

Clopidogrel Bisulfate Uses

Clopidogrel is used to prevent strokes and heart attacks in persons who are at high risk. In one large study, clopidogrel was more effective than aspirin in reducing heart attacks. The frequency of side effects of clopidogrel was similar to aspirin; however, stomach and intestinal bleeding probably occurs less often with clopidogrel than with aspirin.

Clopidogrel Instructions

The usual dose is 75 milligrams once a day. To give people with unstable angina an extra boost, their first dose is usually increased to 300 milligrams. Each dose of Clopidogrel must be taken with a full glass of water of about 6-8 ounces. Clopidogrel is not a stomach irritant so it can be taken on a full or empty stomach.

What precautions should I follow?

Clopidogrel should not be used if you are taking non-steroidal anti-inflammatory drugs without your doctor’s advice such as, buprofen, naproxen, diflunisal. It is better to stop using Clopidogrel immediately if you are suffering from active bleeding disorders such as stomach ulcer or vaginal bleeding. Avoid taking the drug if you spot some allergic reactions in your body.

Clopidogrel side effects

Stomach upset or pain, diarrhea, constipation, headache, dizziness, rash, flu-like symptoms, or back/joint pain may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Clopidogrel rarely causes a condition called thrombotic thrombocytopenic purpura (TTP) in one out of every 250,000 people. TTP is a serious condition in which blood clots form throughout the body. Tell your doctor immediately if any of these signs of serious bleeding occur: