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Rheumatoid arthritis is a chronic inflammatory disease that primarily affects the joints and surrounding tissues, but can also affect other organ systems.
It is the most common type of arthritis which is triggered by the immune system.
Arthritis is a known risk factor for hardening of the arteries and so can lead to stroke and heart attacks ten years earlier than in people without the condition.
The body's immune system normally fights off foreign substances, like viruses. But in an autoimmune disease, the immune system confuses healthy tissue for foreign substances. As a result, the body attacks itself.
A new class of medications, biologic response modifiers, are medications that stimulate or restore the ability of the immune system to fight arthritis and rheumatic disease.
In some cases these pain relief medications are used alone; in many cases, they are combined with methotrexate for added efficacy.
Celecoxib was recently approved by the FDA for acute and chronic use in the relief of the signs and symptoms of rheumatoid arthritis in adults.
Celecoxib is available by prescription in two strengths, 100 mg and 200 mg. The recommended therapeutic dose of Celecoxib for osteoarthritis is 200 mg daily administered as a single dose or 100 mg twice daily. For rheumatoid arthritis, the recommended therapeutic dose is 100 mg to 200 mg, twice daily.
